Title: What vaccines have side effects? Hot topics and data analysis on the entire network
Recently, the discussion about the sequelae of vaccines has once again become a hot topic on the Internet. As vaccination becomes more popular, some users have reported symptoms of discomfort after vaccination, which has aroused public concern about the safety of vaccines. This article combines hot topics and data from the entire Internet in the past 10 days to analyze which vaccines are mentioned as having possible side effects and provide structured data reference.
1. Top 5 vaccine sequelae that are hotly discussed across the Internet

| Vaccine name | Mentions | Feedback on main sequelae | Hot discussion platform |
|---|---|---|---|
| COVID-19 vaccine (various brands) | 12,850 | Fatigue, headache, muscle aches | Weibo, Zhihu |
| HPV vaccine | 5,620 | Irregular menstruation, dizziness | Xiaohongshu, Douban |
| flu vaccine | 3,210 | Low-grade fever, redness and swelling at the injection site | Douyin, Kuaishou |
| rabies vaccine | 2,540 | Arm pain and fever | Baidu Tieba |
| Hepatitis B vaccine | 1,890 | Partial induration and fatigue | WeChat public account |
2. Focus of controversy on vaccine sequelae
1.COVID-19 vaccine controversy: The Weibo topic #新冠vaccines sequelae# has been read 320 million times. Some users reported long-term fatigue or cognitive decline after vaccination, but authoritative organizations stated that most of the symptoms were short-term reactions.
2.HPV vaccine safety discussion: There are more than 20,000 related notes on Xiaohongshu, and young women are the most concerned about it. About 15% reported that they experienced changes in their menstrual cycles after vaccination.
3.Flu vaccine seasonal concerns: As the autumn vaccination season approaches, a large number of vaccination experience sharings appear on short video platforms, and about 8% of the content mentions adverse reactions.
3. Comparison of official data and user feedback
| Vaccine type | official adverse reaction rate | Network feedback rate | Magnitude of difference |
|---|---|---|---|
| COVID-19 inactivated vaccine | 0.12% | 1.8% | +1400% |
| HPV quadrivalent vaccine | 0.08% | 0.6% | +650% |
| seasonal flu vaccine | 0.05% | 0.3% | +500% |
4. Expert interpretation and suggestions
1.Distinguish between normal reactions and sequelae: Medical experts point out that fever and pain within 48 hours after vaccination are mostly normal immune responses, and symptoms that last for more than 2 weeks require medical attention.
2.Rare serious reaction data: According to the WHO monitoring system, the incidence of severe allergic reactions is about one in a million, which is far lower than the rate of online transmission.
3.Notes for special populations: Patients with chronic diseases and immunocompromised people need special evaluation before vaccination, but they should not refuse necessary vaccinations due to choking.
5. User response guide
1. Read the informed consent form carefully before vaccination to understand possible adverse reactions.
2. Observe for 30 minutes after vaccination to record body reactions
3. If persistent symptoms occur, report them through formal channels.
4. Don’t trust individual cases spread on the Internet and refer to large-sample research data
The statistical period of the data in this article: October 1 to October 10, 2023. The data sources include hot topics and public reports on mainstream social platforms such as Weibo, Douyin, and Zhihu. It needs to be emphasized that most adverse reactions to vaccines are mild and short-lived, and the public health benefits of vaccination far outweigh the potential risks. Please consult a professional medical institution for specific health issues.
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